Unique Presentation Identifier:
O14
Program Type
Undergraduate
Faculty Advisor
Dr. Aniruddha Acharya
Document Type
Presentation
Location
Face-to-face
Start Date
29-4-2025 1:00 PM
Abstract
Human immunodeficiency virus poses major health burden across the globe including the United States of America and has its zoonotic origin from the Simian Immunodeficiency viruses of sooty mangabey monkey and chimpanzee in Africa. Epidemiological trends indicate that even though the mortality rates for HIV are falling globally, the rates of new cases have been rising since 2010 in several countries including the USA. An estimated 0.5% of the human population is currently infected with the virus with countries like USA, India, Nigeria and South Africa carrying the highest burden of the disease. Host receptors such as CD4 and coreceptors such as CCR5 and CXCR4 play an important role in the entry of the virus while the viral reverse transcriptase allows the virus to integrate with the host genome and evade host immune system. With the progression of the disease, the host immune system is overwhelmed, and the patient succumbs to secondary infection. Detection of the virus includes antibody assay (IgG, IgM), western blot, antigen detection (recombinant and p24) or simultaneous detection of both antigen and antibody. In the absence of vaccine, antiretroviral drugs have been used to extend life expectancy of patients, CRISPR Cas9-based therapy have shown promise of cure to this devastating disease. Bibliometric analysis indicate Harvard university, Johns Hopkins University and National Institute of Health are the prominent institutes leading research on HIV with NIH being the single most important source of funds for research related to HIV while Bill and Melinda Gates Foundation donates an equivalent amount as the European Union to find cure for the disease.
Recommended Citation
Johnson, Madyson E.; Coffman, Kaitlyn R.; Rivas, Valerie; and Barrett, Elizabeth, "Bibliometric analysis of research trends related to Human Immunodeficiency Virus." (2025). ATU Student Research Symposium. 52.
https://orc.library.atu.edu/atu_rs/2025/2025/52
Included in
Biology Commons, Cell Biology Commons, Other Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons, Pharmacy Administration, Policy and Regulation Commons, Therapeutics Commons, Virology Commons
Bibliometric analysis of research trends related to Human Immunodeficiency Virus.
Face-to-face
Human immunodeficiency virus poses major health burden across the globe including the United States of America and has its zoonotic origin from the Simian Immunodeficiency viruses of sooty mangabey monkey and chimpanzee in Africa. Epidemiological trends indicate that even though the mortality rates for HIV are falling globally, the rates of new cases have been rising since 2010 in several countries including the USA. An estimated 0.5% of the human population is currently infected with the virus with countries like USA, India, Nigeria and South Africa carrying the highest burden of the disease. Host receptors such as CD4 and coreceptors such as CCR5 and CXCR4 play an important role in the entry of the virus while the viral reverse transcriptase allows the virus to integrate with the host genome and evade host immune system. With the progression of the disease, the host immune system is overwhelmed, and the patient succumbs to secondary infection. Detection of the virus includes antibody assay (IgG, IgM), western blot, antigen detection (recombinant and p24) or simultaneous detection of both antigen and antibody. In the absence of vaccine, antiretroviral drugs have been used to extend life expectancy of patients, CRISPR Cas9-based therapy have shown promise of cure to this devastating disease. Bibliometric analysis indicate Harvard university, Johns Hopkins University and National Institute of Health are the prominent institutes leading research on HIV with NIH being the single most important source of funds for research related to HIV while Bill and Melinda Gates Foundation donates an equivalent amount as the European Union to find cure for the disease.