Unique Presentation Identifier:
O1
Program Type
Undergraduate
Faculty Advisor
Aniruddha Acharya
Document Type
Presentation
Location
Face-to-face
Start Date
29-4-2025 9:00 AM
Recommended Citation
Surles, Nathan F., "DELLA protein and CBL-CIPK signaling pathway as candidates for genetic engineering" (2025). ATU Student Research Symposium. 57.
https://orc.library.atu.edu/atu_rs/2025/2025/57
COinS
Apr 29th, 9:00 AM
DELLA protein and CBL-CIPK signaling pathway as candidates for genetic engineering
Face-to-face
Comments
DELLA genes are exclusive to land plants. DELLA proteins are negative regulators of gibberellins and are considered as master growth repressors. Gibberellins mediate the polyubiquitination and degradation of DELLA proteins. Thus, they influence several aspects of plant growth and development such as seed germination, seed development and vegetative growth. DELLA proteins are involved in crosstalk between phytohormones and the environment. DELLAs played a significant role in the green revolution that focused on modification of above-ground parts of plants. Their role in root development is poorly understood though recent reports indicate their role in root development, nodulation and the growth of endodermis. Calcium signaling through CBL-CIPK network plays a major role in plant’s response to developmental and environmental cues. CBL–CIPK is a calcium-dependent signaling pathway that is conserved across plant kingdom. It has a central role in growth, development, ion homeostasis and stress management. The pathway tightly regulates sequestration and release of calcium from the external environment and the intracellular organelles, thus maintaining Ca2+ homeostasis. Thus, investigating genetic networks involving DELLA proteins and CBL-CIPK signaling pathway can identify targets for genetic engineering. Transgenic lines with robust root systems can be developed improving nutrient sequestration. CBL-CIPK and DELLA can serve as excellent genetic engineering candidates for climate-smart agriculture, alleviation of micronutrient deficiency and phytoremediation of heavy metals. Bibliometric analysis indicated the countries, institutes and funding agencies that are heavily involved in this area of research.