Corticosterone response in the chick separation-stress paradigm
Document Type
Article
Publication Date
1-1-2003
Abstract
Corticosterone response to separation stress and its sensitivity to the anxiolytic, chlordiazepoxide (CDP), were examined in 7-day-old domestic fowl (Gallus gallus). Saline or CDP (8.0 mg/kg) was injected intramuscularly 30 min before tests. Chicks were placed in isolation either with or without mirrors for a 15-min observation period, in which distress vocalizations were recorded. After testing, chicks were euthanized and blood was collected for the corticosterone assay. Chicks tested in the No-Mirror condition displayed an increase in vocalizations that was attenuated by CDP. Similarly, corticosterone levels were highest in chicks tested in the No-Mirror condition; however, CDP only modestly attenuated corticosterone levels. The present findings demonstrate that corticosterone levels parallel the behavioral marker of distress vocalizations in this paradigm, but this biological marker may be less sensitive than the behavioral marker to benzodiazepine anxiolytic manipulations. © 2003 Elsevier Science Inc. All rights reserved.
DOI
10.1016/S0031-9384(03)00030-1
First Page
489
Last Page
493
Volume
78
Issue
3
Publication Title
Physiology and Behavior
ISSN
00319384
Recommended Citation
Feltenstein, M. W., Lambdin, L. C., Webb, H. E., Warnick, J. E., Khan, S. I., Khan, I. A., Acevedo, E. O., & Sufka, K. J. (2003). Corticosterone response in the chick separation–stress paradigm. Physiology & Behavior, 78(3), 489–493. https://doi.org/10.1016/s0031-9384(03)00030-1
Comments
At the time of publication, Jason E. Warnick was affiliated with University of Mississippi.